2018

 

2017

Magoulas G.E., Tsigkou T., Skondra L., Lamprou M., Tsoukala P., Kokkinogouli V., Pantazaka E., Papaioannou D., Athanassopoulos C.M. and Papadimitriou E. “Synthesis of novel artemisinin dimers with polyamine linkers and evaluation of their potential as anticancer agents”. Bioorg Med Chem, 25: 3756-3767, 2017.

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2016 

Papadimitriou E.*, Pantazaka E., Castana P., Tsalios T., Polyzos A. and Beis D. “Pleiotrophin and its receptor protein tyrosine phosphatase beta/zeta as regulators of angiogenesis”. Biochim Biophys Acta, 1866: 252-265, 2016.

Tsigkas G., Katsanos K., Apostolakis E., Papadimitriou E., Koutsioumpa M., Kagadis G.C., Koumoundourou D., Hahalis G. and Alexopoulos D. “A minimally invasive endovascular rabbit model for experimental induction of progressive myocardial hypertrophy”. Hypertens Res, 39: 840-847, 2016. 

Sarigiannis Y., Kolokithas-Ntoukas A., Beziere N., Zbořil R., Papadimitriou E., Avgoustakis K., Lamprou M., Medrikova Z., Rousalis E., Ntziachristos V. and Bakandritsos A. “Synthesis and evaluation of condensed magnetic nanocrystal clusters with in vivo multispectral optoacoustic tomography for tumour targeting”. Biomaterials, 91: 128-139, 2016.

Poimenidi E., Theodoropoulou C., Koutsioumpa M., Skondra L., Droggiti E., van den Broek M., Koolwijk P. and Papadimitriou E.* “Vascular endothelial growth factor A (VEGF-A) decreases expression and secretion of pleiotrophin in a VEGF receptor-independent manner”. Vasc Pharmacol, 80: 11-19, 2016.

Kaspiris A., Chronopoulos E., Grivas T.B., Vasiliadis E., Khaldi L., Lamprou M., Lelovas P.P., Papaioannou N., Dontas I.A. and Papadimitriou E.* “Effects of mechanical loading on the expression of pleiotrophin and its receptor protein tyrosine phosphatase beta/zeta in a rat spinal deformity model”. Cytokine, 78: 7-15, 2016.  

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2015 

Giannopoulou E., Nikolakopoulos A., Kotsirilou D., Lampropoulou A., Raftopoulou S., Papadimitriou E., Theocharis A.D., Makatsoris T., Fasseas K. and Kalofonos H.P. “Epidermal growth factor receptor status and Notch inhibition in non-small cell lung cancer cells”. J Biomed Sci, 22: 98, 2015.

Koniari I., Mavrilas D., Apostolakis E., Papadimitriou E., Papadaki H., Papalois A., Poimenidi E., Xanthopoulou I., Hahalis G. and Alexopoulos D. “Inhibition of atherosclerosis progression, intimal hyperplasia, and oxidative stress by simvastatin and ivabradine may reduce thoracic aorta’s stiffness in hypercholesterolemic rabbits”. J Cardiovasc Pharmacol Ther, 21: 412-422, 2015.

Kaspiris A., Khaldi L., Chronopoulos E., Vasiliadis E., Grivas T., Kouvaras I., Dagkas S. and Papadimitriou E. “Macrophage-specific metalloelastase (MMP-12) immunoexpression in the osteochondral unit in osteoarthritis correlates with BMI and disease severity”. Pathophysiology, 22: 143-151, 2015.

Tsirmoula S., Lamprou M., Hatziapostolou M., Kieffer N. and Papadimitriou E.* “Pleiotrophin-induced endothelial cell migration is regulated by xanthine oxidase-mediated generation of reactive oxygen species”. Microvasc Res, 98:74-81, 2015.

Koutsioumpa M., Poimenidi E., Pantazaka E., Theodoropoulou C., Skoura A., Megalooikonomou V., Kieffer N., Courty J., Mizumoto S., Sugahara K. and Papadimitriou E.* “Receptor protein tyrosine phosphatase beta/zeta is a functional binding partner for vascular endothelial growth factor”. Mol Cancer, 14: 19, 2015.  

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2014 

Lamprou M., Kaspiris A., Panagiotopoulos E., Giannoudis P. and Papadimitriou E.* “The role of pleiotrophin in bone repair”. Injury, 45: 1816-1823, 2014.  

Vasiliadis E.S., Kaspiris A., Grivas T.B., Khaldi L, Lamprou M., Pneumaticos S.G., Nikolopoulos K., Korres D.S. and Papadimitriou E. “Expression of macrophage elastase (MMP12) in rat tail intervertebral disc and growth plate during degeneration after asymmetric loading”. Bone Joint Res, 3: 273-279, 2014.

Pantazaka E. and Papadimitriou E*. “Chondroitin sulfate-cell membrane effectors as regulators of growth factor-mediated vascular and cancer cell migration”. Biochim Biophys Acta, 1840: 2643-2650, 2014.

Koutsioumpa M. and Papadimitriou E*. “Cell surface nucleolin as a target for anti-cancer therapies”. Recent Pat Anticancer Drug Discov, 9: 137-152, 2014.

Koniari I., Apostolakis E., Diamantopoulos A., Papadaki H., Papadimitriou E., Poimenidi E., Karnabatidis D., Karahaliou A., Costaridou L., Papalois A., Siablis D., Dougenis D. and Alexopoulos D. “Transauricular balloon angioplasty in rabbit thoracic aorta: a novel model of experimental restenosis”. Lipids Health Dis, 13: 33, 2014.  

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2013 

Kaspiris A., Khaldi L., Grivas T.B., Vasiliadis E., Kouvaras I., Dagkas S., Chronopoulos E. and Papadimitriou E. “Subchondral cyst development and MMP-1 expression during progression of osteoarthritis: an immunohistochemical study”. Orthop Traumatol Surg Res, 99: 523-529, 2013.

Koutsioumpa M., Polytarchou C., Courty J., Zhang Y., Kieffer N., Mikelis C., Skandalis S., Hellman U., Iliopoulos D. and Papadimitriou E.* “Interplay between αvβ3 integrin and nucleolin regulates human endothelial and glioma cell migration”. J Biol Chem, 288: 343-354, 2013.

Kaspiris A., Mikelis C., Heroult M., Khaldi L., Grivas T.B., Kouvaras I., Dangas S., Vasiliadis E., Lioté F., Courty J. and Papadimitriou E.* “Expression of the growth factor pleiotrophin and its receptor protein tyrosine phosphatase beta/zeta in the serum, cartilage and subchondral bone of patients with osteoarthritis”. Joint Bone Spine, 80: 407-413, 2013.

Vourtsis D., Giannou T., Sadikoglou E., Theodorakopoulou O., Sarrou H., Magoulas G., Athanassopoulos C.M., Drainas D., Papaioannou D. and Papadimitriou E.* “Effect of an all–trans-retinoic acid and its conjugate with spermine on human endothelial and prostate cancer cell growth in vitro and angiogenesis in vivo”. Eur J Pharmacol, 698: 122-130, 2013.

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2012 

Pantazaka E. and Papadimitriou E*. PTN (pleiotrophin). Atlas Genet Cytogenet Oncol Haematol, 16: 821-837, 2012.

Tsirmoula S., Dimas K., Hatziapostolou M., Lamprou M., Ravazoula P. and Papadimitriou E.* “Implication of pleiotrophin in human prostate PC3 cancer cell growth in vivo”. Cancer Sci, 103: 1826-32, 2012.

Koutsioumpa M., Drosou G., Mikelis C., Theochari K., Vourtsis D., Katsoris P., Giannopoulou E., Courty J., Petrou C., Magafa V., Cordopatis P. and Papadimitriou E.* “Pleiotrophin expression and role in physiological angiogenesis in vivo: Potential involvement of nucleolin”. Vascular Cell, 4: 4, 2012.  

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2011 

Kouroufexi A., Theophanous-Kitiri S., Polykarpou G., Markou G. and Papadimitriou E. “Clinical evaluation of lenograstim use in the Bank of Cyprus Oncology Centre”. European Journal of Oncology Pharmacy (EJOP), 5: 31-33, 2011.

Lampropoulou E., Manioudaki M., Fousteris M., Koutsourea A., Nikolaropoulos S. and Papadimitriou E.* “Pyrrolo[2,3-α]carbazole derivatives as topoisomerase I inhibitors that affect viability of glioma and endothelial cells in vitro and angiogenesis in vivo”. Biomed Pharmacother, 65: 142-150, 2011.

Mikelis C., Lamprou M., Koutsioumpa M., Koutsioubas A.G., Spyranti Z., Zompra A.A., Spiliopoulos N., Vradis A.A., Katsoris P., Spyroulias G.A., Cordopatis P., Courty J. and Papadimitriou E.* “A peptide corresponding to the C-terminal region of pleiotrophin inhibits angiogenesis in vivo and in vitro”. J Cell Biochem, 112: 1532-1543, 2011.

Friligou I., Papadimitriou E., Gatos D., Matsoukas J. and Tselios T. “Microwave-assisted solid-phase peptide synthesis of the 60-110 domain of human pleiotrophin (hPTN) on 2-chlorotrityl resin”. Amino Acids, 40: 1431-1440, 2011.

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2010 

Mattheolabakis G., Lagoumintzis G., Panagi Z., Papadimitriou E., Partidos C.D. and Avgoustakis K. “Transcutaneous delivery of a nanoencapsulated antigen: Induction of immune responses”. Int J Pharm, 385: 187-193, 2010.

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2009 

Papadimitriou E.*, Mikelis C., Lampropoulou E., Koutsioumpa M., Theochari K., Tsirmoula S., Theodoropoulou C., Lamprou M., Sfaelou E., Vourtsis D. and Mpountouris P. “Role of pleiotrophin in tumor growth and angiogenesis” Eur Cytokine Netw, 20: 180-190, 2009.

Sadikoglou E., Magoulas G., Theodoropoulou C., Athanassopoulos C., Giannopoulou E., Theodorakopoulou O., Drainas D., Papaioannou D.* and Papadimitriou E.* “Effect of conjugates of all-trans-retinoic acid and shorter polyene chain analogues with amino acids on prostate cancer cell growth”. Eur J Med Chem, 44: 3175-3187, 2009.

Mikelis C., Sfaelou E., Koutsioumpa M., Kieffer N. and Papadimitriou E*. “Integrin ανβ3 is a pleiotrophin receptor required for pleiotrophin-induced endothelial cell migration through receptor protein tyrosine phosphatase β/ζ”. FASEB J, 23: 1459-1469, 2009.

Poimenidi E., Hatziapostolou M. and Papadimitriou E*. “Serum stimulates pleiotrophin gene expression and secretion in an AP-1 dependent manner in human endothelial and glioblastoma cells”. Anticancer Res, 29: 349-354, 2009.

Koutsioumpa M., Hatziapostolou M., Mikelis C., Koolwijk P. and Papadimitriou E*. “Aprotinin stimulates angiogenesis and human endothelial cell migration through the growth factor pleiotrophin and its receptor protein tyrosine phosphatase β/ζ”. Eur J Pharmacol, 602: 245-249, 2009.

Polytarchou C., Hatziapostolou M., Poimenidi E., Mikelis C., Papadopoulou A., Parthymou A. and Papadimitriou E*. “Nitric oxide stimulates migration of human endothelial and prostate cancer cells through up-regulation of pleiotrophin expression and its receptor protein tyrosine phosphatase β/ζ”. Int J Cancer, 124: 1785-1793, 2009.  

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2008

Papadimitriou E., Koliakos G. and Karamanos N. “Biochemistry and molecular biology in Greece: history and perspectives”. IUBMB Life, 60: 250-253, 2008.

Mikelis C. and Papadimitriou E*. “Heparin-binding protein pleiotrophin: An important player in the angiogenic process”. Connect Tissue Res, 49: 149-152, 2008.

Fousteris M.A., Vlachopoulos G., Koutsourea A., Manioudaki M., Lampropoulou E., Papadimitriou E., Spyroulias G. and Nikolaropoulos S.S. “Pyrrolo[2,3-a]carbazoles as potential CDK1 inhibitors. Synthesis, preliminary evaluation and binding properties through docking simulations”. J Med Chem, 51: 1048-1052, 2008.

Parthymou A., Lambropoulou E., Mikelis C., Drosou G. and Papadimitriou E*. “Heparin affin regulatory peptide/pleiotrophin interacts with vascular endothelial growth factor and negatively affects tumor growth and angiogenesis induced by glioma cells”. Eur J Cell Biol, 87: 17-29, 2008.  

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2007

Mikelis C., Koutsioumpa M. and Papadimitriou E*. “Pleiotrophin as a possible new target for angiogenesis-related diseases and cancer”. Recent Patents on Anti-Cancer Drug Discovery, 2: 175-186, 2007.

Gryparis E., Hatziapostolou M., Papadimitriou E. and Avgoustakis K. “Anticancer activity of cisplatin-loaded PLGA-mPEG nanoparticles on LNCaP prostate cancer cells”. Eur J Pharm Biopharm, 67: 1-8, 2007.

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2006 

Hatziapostolou M., Polytarchou C., Katsoris P., Courty J. and Papadimitriou E*. “Heparin affin regulatory peptide/pleiotrophin mediates fibroblast growth factor 2 stimulatory effects on human prostate cancer cells”. J Biol Chem, 281: 32217-32226, 2006.

Pyriohou A., Beis D., Koika V., Potytarchou C., Papadimitriou E., Zhou Z. and Papapetropoulos A. “Soluble guanylyl cyclase activation promotes angiogenesis”. J Pharmacol Exp Ther, 319: 663-671, 2006.

Kokolakis G., Mikelis C., Papadimitriou E., Courty J., Karetsou E. and Katsoris P. “Effect of heparin affin regulatory peptide on the expression of vascular endothelial growth factor receptors in endothelial cells”. In vivo, 20: 629-635, 2006.

Polytarchou C., Kardamakis D., Katsoris P and Papadimitriou E*. “Antioxidants modify the effect of X rays on blood vessels”. Anticancer Res, 26: 3043-3047, 2006.  

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2005

Polytarchou C., Hatziapostolou M. and Papadimitriou E*. “Hydrogen peroxide stimulates proliferation and migration of human prostate cancer cells through activation of activator protein-1 and up-regulation of the heparin affin regulatory peptide gene”. J Biol Chem, 280: 40428-40435, 2005.

Polykratis A., Katsoris P., Courty J. and Papadimitriou E*. “Characterization of heparin affin regulatory peptide signaling in human endothelial cells”. J Biol Chem, 280: 22454-22461, 2005.

Hatziapostolou M., Delbe J., Katsoris P., Polytarchou C., Courty J. and Papadimitriou E*. “Heparin affin regulatory peptide is a key player in prostate cancer cell growth and angiogenicity”. Prostate, 65: 151-158, 2005.

Polytarchou C. and Papadimitriou E*. “Antioxidants inhibit human endothelial cell functions through down-regulation of endothelial nitric oxide synthase activity”. Eur J Pharmacol, 510: 31-38, 2005.

Arsenou E., Papadimitriou E., Kliafa E., Hountala M. and Nikolaropoulos S. “Effects of retinoic acid steroidal analogues on human leukemic HL60 cells proliferation in vitro and on angiogenesis in vivo”. Anti-Cancer Drugs, 16: 151-158, 2005.  

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2004 

Papadimitriou E.*, Polykratis A., Hatziapostolou M., Parthymou A., Polytarchou C. and Mikelis C. “Heparin affin regulatory peptide: a new target for tumour therapy?”. Curr Cancer Drug Targets, 4: 471-482, 2004.

Polytarchou C., Gligoris T., Kardamakis D., Kotsaki E. and Papadimitriou E*. “X-rays affect the expression of genes involved in angiogenesis”. Anticancer Res, 24: 2941-2945, 2004.

Loutrari H., Hatziapostolou M., Skouridou V., Papadimitriou E., Roussos C., Kolisis F. and Papapetropoulos A. “Perillyl alcohol inhibits angiogenesis in vitro and in vivo”. J Pharmacol Exp Ther, 311: 568-575, 2004.

Polytarchou C. and Papadimitriou E*. “Antioxidants inhibit angiogenesis in vivo through down-regulation of nitric oxide synthase expression and activity”. Free Radical Res, 38: 501-508, 2004.

Parthymou A., Kardamakis D., Pavlopoulos G. and Papadimitriou E*. “Irradiated C6 glioma cells induce angiogenesis in vivo and activate endothelial cells in vitro”. Int J Cancer, 110: 807-814, 2004.

Polykratis A., Delbe J., Courty J., Papadimitriou E*. and Katsoris P. “Identification of heparin affin regulatory peptide domains with potential role on angiogenesis”. Int J Biochem Cell Biol, 36: 1964-1976, 2004.

Heroult M., Bernard-Pierrot I., Delbe J., Hamma-Kourbali Y., Katsoris P., Barritault D., Papadimitriou E., Plouet J. and Courty J. “Heparin affin regulatory peptide binds to vascular endothelial growth factor (VEGF) and inhibits VEGF-induced angiogenesis”. Oncogene, 23: 1745-1753, 2004.

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2003 

Giannopoulou E. and Papadimitriou E*. “Amifostine has antiangiogenic properties in vitro by changing the redox status of human endothelial cells”. Free Radical Res, 37: 1191-1199, 2003.

Koletsis E., Chatzimichalis A., Fotopoulos V., Kokkinis K., Papadimitriou E., Tiniakos D., Marinos E., Bellenis I. and Dougenis D. “Donor lung pretreatment with surfactant in experimental transplantation preserves graft hemodynamics and alveolar morphology”. Exp Biol Med (Maywood), 228: 540-545, 2003.

Hatziapostolou M., Katsoris P. and Papadimitriou E*. “Different inhibitors of plasmin differentially affect angiostatin production and angiogenesis”. Eur J Pharmacol, 460: 1-8, 2003.

Gortzi O., Antimisiaris S.G., Klepetsanis P., Papadimitriou E. and Ioannou P.V. “Arsonoliposomes: Effect of arsonolipid acyl chain length and vesicle composition on their toxicity towards cancer and normal cells in culture”. Eur J Pharm Sci, 18: 175-183, 2003. 

Lawrence F., Liu J.M., Kovacevic M., Bignon J., Meric P., Papadimitriou E., Lallemand J.Y., Katsoris P., Potier P., Fromes Y. and Wdzieczak-Bakala J. “The tetrapeptide AcSDKP, an inhibitor of primitive hematopoietic cell proliferation, induces angiogenesis in vitro and in vivo”. Blood, 101: 3014-3020, 2003.

Giannopoulou E., Katsoris P., Kardamakis D. and Papadimitriou E*. “Amifostine inhibits angiogenesis in vivo“. J Pharmacol Exp Ther, 304: 729-737, 2003.

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2002 

Giannopoulou E., Katsoris P., Parthymou A., Kardamakis D. and Papadimitriou E*. “Amifostine protects blood vessels from the effects of ionizing radiation“. Anticancer Res, 22: 2821-2826, 2002.

Giannopoulou E., Katsoris P., Polytarchou C. and Papadimitriou E*. “Nitration of cytoskeletal proteins in the chicken embryo chorioallantoic membrane“. Arch Biochem Biophys, 400: 188-198, 2002.

Gortzi O., Papadimitriou E., Kontogiannis C.G., Antimisiaris S.G. and Ioannou P. “Arsonoliposomes: a novel class of arsenic containing liposomes: Effect of palmitoyl-arsonolipid containing liposomes on the viability of cancer and normal cells in culture“, Pharm Res, 19: 79-86, 2002.  

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2001

Kallinteri P., Papadimitriou E. and Antimisiaris S. “Uptake of liposomes which incorporate a glycopeptide fraction of asialofetuin by HepG2 cells”, J Lipos Res, 11: 175-193, 2001.

Giannopoulou E., Katsoris P., Hatziapostolou M., Kardamakis D., Kotsaki E., Polytarchou C., Parthymou A., Papaioannou, S. and Papadimitriou E*. “X rays modulate extracellular matrix in vivo”. Int J Cancer, 94: 690-698, 2001.

Papadimitriou E., Maragoudakis M.E., Waters C., Manolopoulos V.G., Unsworth B.R. and Lelkes P.I. “Regulation of extracellular matrix protein deposition and MMP-2 secretion in cultured endothelial cells”. Endothelium, 8: 243-253, 2001.

Papadimitriou E., Polykratis A., Courty J., Koolwijk P., Heroult M. and Katsoris P. “HARP induces angiogenesis in vivo and in vitro: Implication of N or C terminal peptides”. Biochem Biophys Res Commun, 282: 306-313, 2001.  

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2000 

Papadimitriou E., Heroult M., Courty J., Polykratis A., Stergiou C. and Katsoris P. “Endothelial cell proliferation induced by HARP: implication of N or C terminal peptides”. Biochem Biophys Res Commun, 274: 242-248, 2000.

Papadimitriou E. and Antimisiaris S. “Interactions of PC/Chol and PS/Chol liposomes with human cells in vitro”. J Drug Target, 8: 335-351, 2000.

Pipili-Synetos E., Kritikou S., Papadimitriou E., Athanassiadou A., Flordellis C. and Maragoudakis M.E. “Nitric oxide synthase expression, enzyme activity and NO production during angiogenesis in the chick chorioallantoic membrane”. Br J Pharmacol, 129: 207-213, 2000.  

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Oldies

Pipili-Synetos E., Papadimitriou E*. and Maragoudakis M.E. “Evidence that platelets promote tube formation by endothelial cells in vitro”. Br J Pharmacol, 125: 1252-1257, 1998.

Papadimitriou E., Kritikou D., Mavroidis M., Zacharopoulou A. and Mintzas A. “The heat shock 70 gene family in the Mediterranean fruit fly Ceratitis capitata”. Insect Mol Biol, 7: 279-290, 1998.

Papadimitriou E., Mintzas A., Skoutari M., Dimitracopoulos G. and Anastassiou E.D. “Cholera toxin stimulates human B-cell DR antigen biosynthesis at the level of translation”. Cellular Immunology, 180: 176-184, 1997.

Papadimitriou E., Manolopoulos V.G., Hayman G.T., Maragoudakis M.E., Unsworth B.R., Fenton J.W. and Lelkes P.I. “Thrombin modulates vectorial secretion of extracellular matrix proteins in cultured endothelial cells”. Am J Physiology, 272 (Cell Physiol.41): C1112-C1122, 1997.

Papadimitriou E., Unsworth B.R., Maragoudakis M.E. and Lelkes P.I. “Time-course and quantitation of extracellular matrix maturation in the chick chorioallantoic membrane and in cultured endothelial cells”. Endothelium, 1: 207-219, 1993.

Papadimitriou E. and Lelkes P.I. “Measurement of cell numbers in microtiter culture plates using the fluorescent dye Hoechst 33258”. J Immunol Meth, 162: 41-45, 1993.

Karakioulakis G., Papadimitriu E., Missirlis E. and Maragoudakis M.E. “Effect of bivalent metal ions on collagenase from Clostridium histolyticum”. Biochemistry International, 34: 397-404, 1991.